MOTS-c Peptide – Mitochondrial-Derived Metabolic Research Peptide

MOTS-c (Mitochondrial Open Reading Frame of the 12S rRNA Type-c) is a mitochondrial-derived peptide widely studied in metabolic regulation, cellular energy balance, and mitochondrial signaling research. As a short bioactive peptide encoded within mitochondrial DNA, MOTS-c has gained significant attention in laboratory research exploring metabolism, stress response pathways, and cellular adaptation mechanisms.

What Is MOTS-c Peptide?

MOTS-c is a naturally occurring peptide encoded by mitochondrial DNA and translated within cells. In research settings, it is investigated for its involvement in metabolic homeostasis, insulin signaling pathways, and mitochondrial-to-nuclear communication.

Its unique origin from mitochondrial genetic material makes MOTS-c Peptide an important compound in studies focused on:

• Cellular energy regulation

• Mitochondrial signaling networks

• Adaptive stress-response pathways

• Metabolic pathway modulation

Key Research Areas & Observations

Scientific literature frequently references MOTS-c Peptide in studies related to:

🔬 Metabolic Regulation Research

Explored in laboratory models evaluating glucose metabolism, lipid utilization, and cellular energy balance.

🧬 Mitochondrial Signaling Pathways

Studied for its role in mitochondrial-to-nuclear communication and transcriptional regulation.

⚙️ Cellular Stress Response

Referenced in experimental research analyzing adaptive cellular responses to metabolic stress.

🧪 Gene Expression & Pathway Modulation

Used in molecular biology studies investigating signaling cascades and regulatory protein activation.

Laboratory Applications

MOTS-c peptide is primarily utilized in:

• Metabolic and bioenergetics research

• Mitochondrial function studies

• Cellular adaptation and stress-response experiments

• Molecular and transcriptional pathway analysis

Experimental concentrations vary depending on assay design, model system, and laboratory protocol.

Product Highlights

• High-purity MOTS-c peptide

• Research-grade quality

• No fillers, additives, or excipients

• Manufactured under strict laboratory standards

• Suitable for in vitro and controlled experimental research

MOTS-c ( Mitochondrial Open Reading Frame of the 12S rRNA-c ) is a
mitochondrially encoded research peptide that plays a role in
cellular energy metabolism and metabolic regulation .
In laboratory research, MOTS-c is applied to
study the interaction between mitochondrial activity, insulin signaling, and fatty acid metabolism in vitro. MOTS-c is produced to the highest laboratory standards and verified via
High-Performance Liquid Chromatography (HPLC) to ensure a purity of ≥ 99%.
Each batch is suitable for controlled research environments and biochemical applications.

Important specifications

Research relevance

• Under investigation for its role in cellular energy metabolism, metabolic homeostasis, and stress response .
• Interesting for studies of insulin sensitivity, fatty acid combustion and mitochondrial signaling pathways .
• Promising research model in the study of aging, metabolism and energy balance .